D1.1 | Project Handbook | 1 | SETU | R | CO | M2 |
D1.2 | Data Management Plan | 1 | SETU | R | CO | M6 |
D1.3 | Updated Data Management Plan period 1 | 1 | SETU | R | CO | M12 |
D1.4 | Updated Data Management Plan period 2 | 1 | SETU | R | CO | M30 |
D1.5 | Final Data Management Plan period 3 | 1 | SETU | R | CO | M48 |
D1.6 | Project reports and updated plans year 1 | 1 | SETU | R | CO | M12 |
D1.7 | Project reports and updated plans year 2 | 1 | SETU | R | CO | M24 |
D1.8 | Project reports and updated plans year 3 | 1 | SETU | R | CO | M36 |
D1.9 | Project reports and updated plans year 4 | 1 | SETU | R | CO | M48 |
D1.10 | Technical/scientific review meeting 1 documents | 1 | SETU | R | CO | M12 |
D1.11 | Technical/scientific review meeting 2 documents | 1 | SETU | R | CO | M31 |
D1.12 | Technical/scientific review meeting 3 documents | 1 | SETU | R | CO | M47 |
D2.1 | End-to-end molecular communication chain model for sensing tRNAs, actuation, and release of GDNF. | 2 | SETU | R | PU | M24 |
D2.2 | AI algorithm for logic gates and device design | 2 | SETU | R | PU | M36 |
D2.3 | Repository for Simulation codes | 2 | SETU | ORDP | PU | M12 |
D3.1 | ARPE-19 cells that express GDNF under the regulation of miRNA | 3 | AU | DEM | PU | M12 |
D3.2 | ARPE-19 cells that express GDNF under the regulation of tsRNA through miRNA | 3 | AU | DEM | PU | M18 |
D3.3 | ARPE-19 cells that express GDNF under both tsRNA and Ca2+ control (AND/OR gate function) | 3 | AU | DEM | PU | M24 |
D4.1 | A characterised set of biocompatible amalgamated/hybrid scaffolds | 4 | TAU | R | PU | M36 |
D4.2 | A reproducible and controllable microenvironment for the ARPE-19 maturation | 4 | TAU | R | PU | M40 |
D4.3 | Design of membrane encapsulation device | 4 | TAU | R | PU | M24 |
D5.1 | Encapsulated device validated in vivo | 5 | RCSI | R | PU | M36 |
D5.2 | Encapsulated device tested in rats | 5 | RCSI | R | PU | M44 |
D5.3 | Encapsulated device tested in mice | 5 | RCSI | R | PU | M44 |
D5.4 | Molecular characterisation and functionality of the explanted device | 5 | RCSI | R | PU | M48 |
D6.1 | Initial Dissemination and exploitation Plan | 6 | EPOS | R | PU | M7 |
D6.2 | Updated Dissemination and exploitation Plan period 1 | 6 | EPOS | R | PU | M12 |
D6.3 | Updated Dissemination and exploitation Plan period 2 | 6 | EPOS | R | PU | M30 |
D6.4 | Final Dissemination and exploitation Plan period 1 | 6 | EPOS | R | PU | M48 |
D7.1 | HCT-Requirement No. 1 | 7 | SETU | Ethics | CO | M4 |
D7.2 | A-Requirement No. 2 | 7 | SETU | Ethics | CO | M1 |
D7.3 | EPQ-Requirement No. 4 | 7 | SETU | Ethics | CO | M1 |