EU Fet Open PRIME was identified by the European Commission as a project of significant interest to feature on the CORDIS – EU Research Results website.
The high profile website features ‘Results in Brief’ which focuses on the progress of selected projects, to highlight the research and results achieved so far. Content on the CORDIS website is translated into six languages.
This recognition of the work of the PRIME project consortium of partners is fantastic, and a proud achievement by the team as we enter the final months of the project and work towards the conclusion of PRIME.
Extract from the article:
Autonomous implantable living cell systems
The PRIME project sought to address this challenge through a pioneering novel technique. Bringing together seven expert international partners in multidisciplinary fields including synthetic biology, computer science, communication engineering and nanomedicine, the project set out to develop an autonomous implantable living cell system, capable of actuating epileptic seizure suppression.
The idea is that these cells, implanted into the brain, can predict epileptic seizures and release therapeutic molecules in real time. A key focus of the project involved modelling and simulating the molecular communication pathways relevant to the onset of epileptic seizure. This was led by the Walton Institute at SETU. Aarhus University focused on the regulation of gene expression and the onset of epileptic seizure, while the Royal College of Surgeons in Ireland looked into the molecular design, implementation and functional validation of engineered neural cells. At the University of Ferrara, scientists investigated engineering mammalian cells with molecular computing functions.
Project partners Tampere University provided expertise in microfabrication, membrane technology and encapsulation of the biocomputing cells. Meanwhile, project partner omiics used their expertise in low-input RNA sequencing and bioinformatics analysis, while EPOS-IASIS provided insights into nanomanufacturing, nanomaterials, nanomedicine and genetic technologies.
Read the article in full here:
About PRIME:
EU FET OPEN PRIME project is funded by the European Commission’s Horizon 2020 Research and Innovation programme. The PRIME project aims to prevent epileptic seizures by developing autonomous implantable living cell systems for the brain.
Led by Walton Institute at South East Technological University PRIME project’s consortium of European partners is made up of Tampere University Finland, Università degli Studi di Ferrara Italy, EPOS-IASIS Cyprus, Aarhus University Denmark, omiics Denmark and Royal College of Surgeons in Ireland (RCSI).
